Mets vs. Guardians Prediction, Odds, Picks – August 6 Updated Aug. 6, 2025 1:00 p.m. ET sharefacebookxredditlink Data Skrive Daniel Schneemann and the Cleveland Guardians take the field against Pete Alonso and the New York Mets at Citi Field on Wednesday at 1:10 p.m. ET. The Mets are -181 moneyline favorites for this matchup against the Guardians (+150). New York is a 1.5-run favorite (at +121 odds). The over/under is 7.5 runs for this game (with -109 odds on the over and -111 odds on the under). Take a look at everything you need from a betting perspective on the Mets-Guardians game, regarding the run line, moneyline and total, plus expert picks.Keep up with MLB on FOX Sports.Guardians vs. Mets Highlights | MLB on FOX Check out the best moments from this MLB matchup between the Cleveland Guardians and the New York Mets. ADVERTISEMENT Mets vs. Guardians Game Information & OddsWhen: Wednesday, August 6, 2025 at 1:10 p.m. ETWhere: Citi Field in Queens, New YorkHow to watch on TV: MLB Network, SNY, and CLEG Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Mets -181 +150 7.5 -109 -111 -1.5 +121 -144 Mets vs. Guardians PredictionScore Prediction: Mets 5, Guardians 4Total Prediction: Over 7.5 runsWin Probabilities: Mets 54%, Guardians 46%Mets vs. Guardians Betting InsightsThe Mets have won 50, or 61.7%, of the 81 games they’ve played as favorites this season.New York has a record of 21-5, a 80.8% win rate, when favored by -181 or more by sportsbooks this season.Sportsbooks have implied with the moneyline set for this matchup that the Mets have a 64.4% chance to win.The Guardians have been victorious in 28, or 43.8%, of the 64 contests they have been chosen as underdogs in this season.This season, Cleveland has come away with a win three times in 11 chances when named as an underdog of at least +150 or worse on the moneyline.Oddsmakers have implied with the moneyline set for this matchup that the Guardians have a 40% chance of pulling out a win.Mets Recent Betting PerformanceThe Mets played as the moneyline favorite for seven of their last 10 games, and went 2-5 in those matchups.Over their last 10 matchups, the Mets and their opponents combined to hit the over on the run total four times (all 10 games had set totals).The Mets have gone 3-7-0 against the spread over their past 10 games. Mets Recent Stats Stat Avg/Total Record 3-7 Runs Per Game 4.1 HR 8 ERA 4.94 K/9 8.5 Mets Player InsightsJuan Soto leads the Mets with 25 home runs.Among all hitters in the majors, Soto ranks 11th in homers and 37th in RBI.Alonso has shown off his power as he paces his team with 25 home runs and 91 runs batted in, with a team-best .267 batting average.Alonso is 11th in homers in the majors, and second in RBI.Alonso has two straight games with at least one hit. In his last five games he is batting .421 with a double, three home runs, two walks and 10 RBIs.Francisco Lindor has 22 doubles, 21 home runs and 37 walks while hitting .251.Brandon Nimmo is hitting .255 with 21 doubles, 19 home runs and 34 walks.Mets Team Props Hits O/U Total Bases O/U HR O/U RBI O/U Pete Alonso 0.5 (-195) 1.5 (+135) – 0.5 (+165) Juan Soto 0.5 (-190) 1.5 (+130) – 0.5 (+170) Jeff McNeil 0.5 (-195) 1.5 (+140) – 0.5 (+200) Francisco Lindor 0.5 (-205) 1.5 (+125) – 0.5 (+200) Ronny Mauricio – – – – Guardians Recent Betting PerformanceThe Guardians have played as underdogs in four of their past 10 games and have gone 3-1 in those contests.In their last 10 games with a total, the Guardians and their opponents are 6-4-0 when it comes to hitting the over.The Guardians have five wins against the spread in their last 10 chances. Guardians Recent Stats Stat Avg/Total Record 7-3 Runs Per Game 5 HR 10 ERA 3.07 K/9 9.8 Guardians Player InsightsJose Ramirez leads the lineup with a batting average of .296, while pacing the Guardians in home runs, with 23 and runs batted in with 61.Ramirez’s home run total places him 15th in the big leagues, and he ranks 45th in RBI.Steven Kwan is hitting .285 with 20 doubles, a triple, nine home runs and 40 walks.Among all major league hitters, Kwan ranks 163rd in home runs and 155th in RBI.Carlos Santana is hitting .229 with eight doubles, 11 home runs and 47 walks.Kyle Manzardo is batting .235 with 13 doubles, two triples, 18 home runs and 33 walks.Guardians Team Props Hits O/U Total Bases O/U HR O/U RBI O/U Steven Kwan 0.5 (-225) 1.5 (+155) – 0.5 (+285) José Ramírez 0.5 (-225) 1.5 (+125) – 0.5 (+185) Nolan Jones – – – – Gavin Williams – – – – Gabriel Arias 0.5 (-165) – – 0.5 (+245) Guardians vs. Mets Highlights | MLB on FOX Check out the best moments from this MLB matchup between the Cleveland Guardians and the New York Mets. 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